Open funding:
Open funding:

Longitudinal study of health and aging in Kenya (LOSHAK)

Africa is aging. While the continent is home to the world's youngest population today, adults over 60 are expected to grow from 5.6% to over 15% of Africa's population by 2050—a demographic transformation that will reshape health systems, social structures, and economic policy across the region. Kenya alone expects its elderly population to quadruple within that same timeframe. Yet population-level data on aging in Kenya and across sub-Saharan Africa remains critically limited, leaving researchers, clinicians, and policymakers without the evidence needed to understand aging trajectories, anticipate care needs, or design effective interventions. Key conditions associated with aging—including Alzheimer's disease and related dementias, mental health disorders, and climate- and pollution-related illness—are poorly characterized in the Kenyan context. Without longitudinal data tracking individuals over time, the risk factors shaping health, disability, and well-being in older Kenyan adults cannot be identified or addressed.

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The Longitudinal Study of Health and Aging in Kenya (LOSHAK) responds to this gap by establishing a establishing a nationally representative cohort study of Kenyan adults aged 45 and older that will eventually enroll thousands of participants and follow them over the course of years. LOSHAK is co-led by Anthony Ngugi of AKU and Joshua Ehrlich of the University of Michigan, whose partnership exemplifies CGHE's model of truly co-designed, equity-centered international collaboration. LOSHAK is also part of the Health and Retirement Study (HRS) global network—a family of aging studies operating in 45 countries—making it only the second such study on the African continent. All data collected will be made publicly available, consistent with HRS network standards.

Current NIH pilot funding supports the groundwork necessary to launch the full-scale study, including refining data collection infrastructure, building community trust in areas new to research partnerships, and developing methods to reach both rural and urban populations across Kenya's diverse geography. Key research focus areas include Alzheimer's disease and related dementias, mental health, the health and economic impacts of extreme weather and air pollution, and factors influencing late-life economic well-being.

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Expected outcomes include a fully operational longitudinal cohort study with national representation; population-level data informing Kenyan health and aging policy; pioneering analysis of the connections between extreme weather, aging, and health in sub-Saharan Africa; peer-reviewed scholarship contributing to global aging research; and publicly available datasets accessible to researchers worldwide. By centering Kenyan researchers and institutions as equal partners in study design and implementation, LOSHAK advances both the science of aging and a model of international collaboration grounded in mutual respect and shared capacity. Learnings from LOSHAK will be widely applicable beyond Kenya, including to aging population in the US, where many of the same exposures and stressors affect older adults.

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Start Date

January 1, 2022

End Date

December 1, 2027

Location

Kenya

Project Investigators

Joshua Ehrlich, MD, MPH

Associate Professor

Medical School
Ophthalmology and Visual Sciences
Anthony Ngugi, PhD, MSc

Associate Professor of Epidemiology and Population Health, Aga Khan University, Kenya

Collaborating Organizations

Aga Khan University
Kenya
Kenya Ministry of Health
Kenya
Kenya National Bureau of Statistics
Kenya
Kenya Medical Research Institute
Kenya
Johns Hopkins University
United States
University of California, Los Angeles
United States
University of California, San Francisco
United States
Georgetown University
United States
Emory University
United States
University of California, Berkeley
United States

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